Phase 9: Research; Chapter 1: Wearing the Hat

Coat the vase in a cocktail of the world's seventeen deadliest poisons, cover the surface in tons of imperceptible pricks to pierce the skin, and for good measure, have a thin layer of explosive in the middle to remote explode it, with the hope that at least one of those poison-laced shards scratch him.

Or just leave him until your sortof secret plans to defeat him are properly ready.